Common Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Hepatitis (viral infection of liver), Jaundice.

Expert advice for Isonij Tablet
Take it on an empty stomach (if it upsets your stomach, take it with food). Take it as and when prescribed (in case you skip a dose, do not take two doses at one time). In order to kill the TB bacteria and cure the disease completely, you will have to take this medicine for 6 to 12 months (your doctor will the precise duration for which you will take the medicine). You need to take vitamin B6 (Pyridoxine) along with Isonij. Vitamin B6 (Pyridoxine) will prevent possible numbness and tingling fingers and toes that may be caused by Isonij.

Q. Is Isonij an antibiotic?
Isonij is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Isonij chemotherapy/chemotherapy drug?
Isonij is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Is Isonij bacteriostatic or bactericidal?
Isonij is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth

Q. Is Isonij safe?
Yes. Isonij is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Isonij a MAOI?
Isonij has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)

Q. Is Isonij a sulfa drug?
No. The chemical structure and mechanism of action of Isonij is different from sulfa drugs

Q. Is Isonij an inducer or inhibitor?
Isonij is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Q. Does Isonij cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isonij. You may experience few of these side effects while on multi drug (including Isonij) treatment for tuberculosis

Q. Does Isonij cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Isonij. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Q. Does Isonij affect birth control?
Isonij has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.